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Finasteride and Dutasteride: What's the Difference?

 what's the difference between finasteride and Dutasteride

What's the difference between finasteride and Dutasteride?


Question from D. Conway.

I am in my 30s, experiencing early stages of male pattern baldness. I was looking at treatments for male hair loss, and finasteride is something that I am considering. However, I came across a similar treatment called Dutasteride, which appears to be not much different to finasteride.

My question is: Is there actually a difference between finasteride and Dutasteride, and if so, what is it? Which one of the two treatments should I take?

Answer:

Finasteride and Dutasteride are both medications used to treat conditions related to the prostate gland in men. They are also used to treat male pattern baldness. However, there are some differences between these two drugs, which are: 

Mechanism of Action: Finasteride and Dutasteride both work by inhibiting the enzyme 5-alpha-reductase, which converts testosterone to dihydrotestosterone (DHT). However, Dutasteride inhibits both types of 5-alpha-reductase enzymes (type 1 and type 2), while finasteride inhibits only the type 2 enzyme.

Treatment of Medical Conditions: Both finasteride and Dutasteride are used to treat benign prostatic hyperplasia (BPH), a condition in which the prostate gland enlarges and causes urinary problems. Finasteride is also used to treat male pattern baldness (androgenetic alopecia), while Dutasteride is not approved for this indication.

Dosage and Administration: Finasteride is usually taken as a 1 mg tablet once a day, while dutasteride is usually taken as a 0.5 mg capsule once a day. Dutasteride has a longer half-life than finasteride, which means it stays in the body for a longer time.

Side Effects: The side effects of finasteride and dutasteride are similar and can include decreased libido, erectile dysfunction, decreased ejaculate volume, and gynecomastia (breast enlargement). However, dutasteride has been associated with a higher incidence of sexual side effects compared to finasteride.

Contraindications: Both finasteride and Dutasteride are contraindicated in pregnant women due to the risk of birth defects. However, Dutasteride may also be more dangerous for women of childbearing age who come into contact with the drug, as it stays in the body for a longer time than finasteride. Therefore, it is recommended that women avoid handling Dutasteride capsules to minimise the risk of exposure.

Always consult with your doctor before using medications. 

Safe alternatives: As far as oral tablets go, the safe alternative to medications like finasteride and Dutasteride is HR23+. HR23+ is a multi-macro-extract supplement that works at the root cause of hair loss. It is safe to use, and highly effective for treating hair loss in men and women with early stages of thinning hair. 

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