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Topical Finasteride Male Baldness Treatment: Does It Work?

Topical finasteride male baldness treatment

How effective is topical finasteride male baldness treatment? 


Topical finasteride refers to a formulation of the medication finasteride that is applied directly to the scalp as a solution or gel, rather than taken orally in pill form. Finasteride is a medication primarily used to treat benign prostatic hyperplasia (BPH) and male pattern baldness (androgenetic alopecia). 

It works by inhibiting the enzyme 5-alpha reductase, which converts testosterone into dihydrotestosterone (DHT), a hormone implicated in the miniaturisation of hair follicles in individuals with androgenetic alopecia.

Topical finasteride has gained attention as an alternative to oral finasteride for treating hair loss, particularly in men, due to its potential to minimise systemic side effects associated with oral administration, such as sexual dysfunction. 

By applying the medication directly to the scalp, the systemic absorption of finasteride is reduced, potentially decreasing the risk of systemic side effects while still effectively targeting DHT levels in the scalp.

Studies evaluating the efficacy and safety of topical finasteride have shown promising results, suggesting it can be effective in halting or even reversing hair loss with potentially fewer systemic side effects compared to oral finasteride. However, more research is needed to fully understand its long-term effectiveness and safety profile.


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Potential side-effects from topical finasteride


While topical finasteride is often considered to have a reduced risk of systemic side effects compared to oral finasteride due to lower systemic absorption, it may still cause local side effects at the site of application. Some potential side effects of topical finasteride may include:

Scalp irritation


Topical solutions or gels may sometimes cause irritation, redness, itching, or burning sensation at the application site. This is one of the most common side effects reported with topical medications.

Allergic reactions


Some individuals may experience allergic reactions to the components of the topical formulation, leading to symptoms such as rash, hives, or swelling of the face, lips, or tongue.

Changes in hair texture


In some cases, individuals may notice changes in the texture or quality of their hair, such as dryness, brittleness, or increased oiliness.

Scalp dryness or flakiness


Topical finasteride may contribute to dryness or flakiness of the scalp in some individuals.

Shedding


Initially, some individuals may experience increased shedding of hair before experiencing the regrowth phase. This shedding is often temporary and may be part of the hair growth cycle adjustment.

It's important to note that while systemic side effects like sexual dysfunction are less common with topical finasteride compared to oral finasteride, they cannot be completely ruled out, especially with long-term use or in individuals who are particularly sensitive to the medication. 

Additionally, individual responses to medications can vary, so not everyone will experience the same side effects.


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How effective is topical finasteride? 


The effectiveness of topical finasteride in treating male pattern baldness (androgenetic alopecia) has been a subject of study and debate. While oral finasteride has been widely used and studied for this purpose, topical formulations have gained attention as a potential alternative, particularly for individuals concerned about systemic side effects associated with oral administration.

Several studies have investigated the efficacy of topical finasteride in comparison to oral finasteride or placebo (inactive substance) in reducing hair loss and promoting hair regrowth. Overall, the results have been promising, suggesting that topical finasteride can be effective in treating androgenetic alopecia.

Here are some key findings from research studies on the effectiveness of topical finasteride:

Hair Count and Density

Studies have shown that topical finasteride can lead to increased hair count and density in individuals with androgenetic alopecia. In some cases, the improvement has been comparable to that achieved with oral finasteride.


Scalp DHT Levels


Topical finasteride has been found to effectively reduce dihydrotestosterone (DHT) levels in the scalp, similar to oral finasteride. Since DHT is implicated in the miniaturization of hair follicles in androgenetic alopecia, lowering its levels can help slow down hair loss and promote hair regrowth.


Duration of Treatment


The optimal duration of treatment with topical finasteride may vary among individuals. Some studies have shown sustained improvements in hair growth with long-term use, while others have suggested that treatment may need to be continued indefinitely to maintain results.

It's important to note that while research indicates the effectiveness of topical finasteride in treating androgenetic alopecia, individual responses to the medication can vary. Factors such as age, the extent of hair loss, and underlying health conditions may influence treatment outcomes.

Summary 


It's important for individuals considering topical finasteride to consult with a healthcare professional to determine the most suitable treatment approach based on their specific needs and medical history. 

Additionally, like any medication, topical finasteride may still have potential side effects or contraindications, so it's essential to use it under medical supervision.

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